EGF-06605 Red

COC(=O)CC(NC(=O)Cc1ccccc1)(NC(=O)c1ccccc1)C(=O)O
0.262
Platform Score
2D Structure
EGF-06605
C20H20N2O6 | Exact mass: 384.1321
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
122
TPSA
384
MW
3
HBD
1.1
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight384.40 Da
TPSA121.8 A^2
HBD3
HBA5
SlogP1.12
Fsp30.200
Rotatable Bonds8
Rings2 (2 aromatic)
QED0.463
SA Score2.87 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC20H20N2O6
Exact Mass384.1321
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes