EGF-06610 Red

O=C(NCCCn1ccnc1)c1cnn(-c2nccc(-c3ccccc3F)n2)c1C1CC1
0.322
Platform Score
2D Structure
EGF-06610
C23H22FN7O | Exact mass: 431.187
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
90
TPSA
432
MW
1
HBD
3.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight431.50 Da
TPSA90.5 A^2
HBD1
HBA7
SlogP3.36
Fsp30.261
Rotatable Bonds8
Rings5 (4 aromatic)
QED0.432
SA Score2.63 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H22FN7O
Exact Mass431.187
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes