EGF-06645 Red

NS(=O)(=O)c1ccc(NC(=O)NCCCc2c[nH]c3ccccc23)cc1
0.330
Platform Score
2D Structure
EGF-06645
C18H20N4O3S | Exact mass: 372.1256
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
117
TPSA
372
MW
4
HBD
2.6
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight372.40 Da
TPSA117.1 A^2
HBD4
HBA3
SlogP2.57
Fsp30.167
Rotatable Bonds6
Rings3 (3 aromatic)
QED0.498
SA Score2.00 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC18H20N4O3S
Exact Mass372.1256
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes