EGF-06775 Red

CCOc1ccccc1C1=Nn2c(Cc3ccc(Br)cc3)nnc2SC1
0.360
Platform Score
2D Structure
EGF-06775
C19H17BrN4OS | Exact mass: 428.0306
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
52
TPSA
429
MW
0
HBD
4.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight429.30 Da
TPSA52.3 A^2
HBD0
HBA6
SlogP4.39
Fsp30.211
Rotatable Bonds5
Rings4 (3 aromatic)
QED0.604
SA Score2.55 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC19H17BrN4OS
Exact Mass428.0306
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes