EGF-06923 Red

Cc1csc(CN2C(=O)c3cccc(N4CCC(S(=O)(=O)c5c(Cl)cccc5Cl)C4)c3C2=O)n1
0.279
Platform Score
2D Structure
EGF-06923
C23H19Cl2N3O4S2 | Exact mass: 535.0194
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
88
TPSA
536
MW
0
HBD
4.6
SlogP
Display Controls
Rotate: drag | Zoom: scroll | Pan: right-drag | Double-click: center Loading...
EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight536.50 Da
TPSA87.7 A^2
HBD0
HBA7
SlogP4.61
Fsp30.261
Rotatable Bonds5
Rings5 (3 aromatic)
QED0.443
SA Score3.29 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC23H19Cl2N3O4S2
Exact Mass535.0194
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes