EGF-07071 Red

COc1cc(-c2cn(-c3ccc4ccccc4c3)nn2)cc(OC)c1OC
0.358
Platform Score
2D Structure
EGF-07071
C21H19N3O3 | Exact mass: 361.1426
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
58
TPSA
361
MW
0
HBD
4.1
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight361.40 Da
TPSA58.4 A^2
HBD0
HBA6
SlogP4.11
Fsp30.143
Rotatable Bonds5
Rings4 (4 aromatic)
QED0.535
SA Score2.17 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC21H19N3O3
Exact Mass361.1426
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes