EGF-07119 Red

C#Cc1cccc(Nc2c(Nc3c(N=O)[nH]c4ccccc4c3=O)c(=O)c2=O)c1
0.290
Platform Score
2D Structure
EGF-07119
C21H12N4O4 | Exact mass: 384.0859
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
1
Hinge Binder
120
TPSA
384
MW
3
HBD
3.0
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight384.40 Da
TPSA120.5 A^2
HBD3
HBA7
SlogP2.99
Fsp3-
Rotatable Bonds5
Rings4 (4 aromatic)
QED0.276
SA Score3.05 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC21H12N4O4
Exact Mass384.0859
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder 4-Aminoquinazoline Hinge
InChIKey-
Filter PassYes