EGF-07140 Red

OC1(CNCc2ccnn2Cc2ccccc2)CCc2c(Cl)ccc3cccc1c23
0.314
Platform Score
2D Structure
EGF-07140
C25H24ClN3O | Exact mass: 417.1608
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
50
TPSA
418
MW
2
HBD
4.7
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight417.90 Da
TPSA50.1 A^2
HBD2
HBA4
SlogP4.66
Fsp30.240
Rotatable Bonds6
Rings5 (4 aromatic)
QED0.479
SA Score3.17 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC25H24ClN3O
Exact Mass417.1608
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes