EGF-07154 Red

O=C(c1cn(Cc2ccccc2)c(=O)c2ccccc12)N1CCN(c2ccccc2F)CC1
0.357
Platform Score
2D Structure
EGF-07154
C27H24FN3O2 | Exact mass: 441.1853
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
46
TPSA
442
MW
0
HBD
4.2
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight441.50 Da
TPSA45.6 A^2
HBD0
HBA4
SlogP4.15
Fsp30.185
Rotatable Bonds4
Rings5 (4 aromatic)
QED0.478
SA Score2.08 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC27H24FN3O2
Exact Mass441.1853
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes