EGF-07227 Red

CC(=NNC(=O)NC1=NCCN1)c1ccc(Br)cc1
0.329
Platform Score
2D Structure
EGF-07227
C12H14BrN5O | Exact mass: 323.0382
Key Metrics
N/A
Vina (kcal/mol)
#-
Docking Rank
0
Hinge Binder
78
TPSA
324
MW
3
HBD
1.4
SlogP
Display Controls
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EGFR Docking Result
N/A
kcal/mol (molecular docking)
Docking Rank#- of 1,249
Consensus Score-
ReceptorEGFR (PDB: 1M17)
Selective No
Selectivity Profile
ADMET Profile
BBB (BOILED-Egg) BBB- (non-penetrant)
ADMET Status Pass (no hard fails)
CNS Drug-Likeness
Physicochemical Properties
Molecular Weight324.20 Da
TPSA77.9 A^2
HBD3
HBA4
SlogP1.43
Fsp30.250
Rotatable Bonds2
Rings2 (1 aromatic)
QED0.568
SA Score2.61 (1=easy, 10=hard)
CNS MPO- / 4.0
FormulaC12H14BrN5O
Exact Mass323.0382
Classification
Scaffold (Murcko)-
Source Versions-
Best Source Score-
Best Source Rank#-
Hinge Binder Not present
InChIKey-
Filter PassYes